Cross Nearest Neighbour Distance — CrossNNDistance • phenoscapR

Computes the nearest neighbour distance from each cell of one phenotype to cells of another phenotype.

Usage

CrossNNDistance(object, from, to)

Arguments

object: An SpatialCellData-class object.
from: Character. Source phenotype.
to: Character. Target phenotype.

Value

A numeric vector of distances (one per cell of the from phenotype).

Examples

counts <- matrix(rnorm(60), nrow = 30,
                 dimnames = list(NULL, c("CD3", "CD8")))
coords <- data.frame(x = runif(30, 0, 100), y = runif(30, 0, 100))
meta <- data.frame(cell_id = 1:30, sample_id = "s1",
  phenotype = rep(c("A", "B", "C"), each = 10))
obj <- CreateSpatialObject(counts, coords, meta)
CrossNNDistance(obj, from = "A", to = "B")
#>  [1] 44.260797 15.592192 33.997372 40.314488 28.982696 14.430704  4.522267
#>  [8] 21.991067 14.004335 11.933756